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Comparison in a rat thigh abscess model of imipenem, meropenem and cefoperazone-sulbactam against Acinetobacter baumannii strains in terms of bactericidal efficacy and resistance selection

BACKGROUND: We compared imipenem, meropenem and cefoperazone-sulbactam against hospital originated A. baumannii strains in terms of bactericidal efficacy and selection of resistant mutants during treatment in a rat thigh abscess model. METHODS: A total of 18 strains were inoculated in 54 animals (on...

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Detalles Bibliográficos
Autores principales: Fetiye, Kolayli, Karadenizli, Aynur, Okay, Erdem, Oz, Sarpkaya, Budak, Fatma, Gundes, Sibel, Vahaboglu, Haluk
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC328090/
https://www.ncbi.nlm.nih.gov/pubmed/14713318
http://dx.doi.org/10.1186/1476-0711-3-2