Low-mutation-rate, reduced-genome Escherichia coli: an improved host for faithful maintenance of engineered genetic constructs

BACKGROUND: Molecular mechanisms generating genetic variation provide the basis for evolution and long-term survival of a population in a changing environment. In stable, laboratory conditions, the variation-generating mechanisms are dispensable, as there is limited need for the cell to adapt to adv...

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Detalles Bibliográficos
Autores principales: Csörgő, Bálint, Fehér, Tamás, Tímár, Edit, Blattner, Frederick R, Pósfai, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280934/
https://www.ncbi.nlm.nih.gov/pubmed/22264280
http://dx.doi.org/10.1186/1475-2859-11-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280934/
https://www.ncbi.nlm.nih.gov/pubmed/22264280
http://dx.doi.org/10.1186/1475-2859-11-11

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