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The Role of Conserved Waters in Conformational Transitions of Q61H K-ras
To investigate the stability and functional role of long-residence water molecules in the Q61H variant of the signaling protein K-ras, we analyzed all available Ras crystal structures and conformers derived from a series of independent explicit solvent molecular dynamics (MD) simulations totaling 1....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280954/ https://www.ncbi.nlm.nih.gov/pubmed/22359497 http://dx.doi.org/10.1371/journal.pcbi.1002394 |