Dynamic Energy Landscapes of Riboswitches Help Interpret Conformational Rearrangements and Function

Riboswitches are RNAs that modulate gene expression by ligand-induced conformational changes. However, the way in which sequence dictates alternative folding pathways of gene regulation remains unclear. In this study, we compute energy landscapes, which describe the accessible secondary structures f...

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Detalles Bibliográficos
Autores principales: Quarta, Giulio, Sin, Ken, Schlick, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280964/
https://www.ncbi.nlm.nih.gov/pubmed/22359488
http://dx.doi.org/10.1371/journal.pcbi.1002368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280964/
https://www.ncbi.nlm.nih.gov/pubmed/22359488
http://dx.doi.org/10.1371/journal.pcbi.1002368

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