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Dynamic Energy Landscapes of Riboswitches Help Interpret Conformational Rearrangements and Function
Riboswitches are RNAs that modulate gene expression by ligand-induced conformational changes. However, the way in which sequence dictates alternative folding pathways of gene regulation remains unclear. In this study, we compute energy landscapes, which describe the accessible secondary structures f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280964/ https://www.ncbi.nlm.nih.gov/pubmed/22359488 http://dx.doi.org/10.1371/journal.pcbi.1002368 |