On the Use of Gene Ontology Annotations to Assess Functional Similarity among Orthologs and Paralogs: A Short Report

A recent paper (Nehrt et al., PLoS Comput. Biol. 7:e1002073, 2011) has proposed a metric for the “functional similarity” between two genes that uses only the Gene Ontology (GO) annotations directly derived from published experimental results. Applying this metric, the authors concluded that paralogo...

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Detalles Bibliográficos
Autores principales: Thomas, Paul D., Wood, Valerie, Mungall, Christopher J., Lewis, Suzanna E., Blake, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280971/
https://www.ncbi.nlm.nih.gov/pubmed/22359495
http://dx.doi.org/10.1371/journal.pcbi.1002386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280971/
https://www.ncbi.nlm.nih.gov/pubmed/22359495
http://dx.doi.org/10.1371/journal.pcbi.1002386

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