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Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection
In most transmissible spongiform encephalopathies prions accumulate in the lymphoreticular system (LRS) long before they are detectable in the central nervous system. While a considerable body of evidence showed that B lymphocytes and follicular dendritic cells play a major role in prion colonizatio...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280992/ https://www.ncbi.nlm.nih.gov/pubmed/22359509 http://dx.doi.org/10.1371/journal.ppat.1002538 |