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Plasmacytoid Dendritic Cells Sequester High Prion Titres at Early Stages of Prion Infection

In most transmissible spongiform encephalopathies prions accumulate in the lymphoreticular system (LRS) long before they are detectable in the central nervous system. While a considerable body of evidence showed that B lymphocytes and follicular dendritic cells play a major role in prion colonizatio...

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Detalles Bibliográficos
Autores principales: Castro-Seoane, Rocio, Hummerich, Holger, Sweeting, Trevor, Tattum, M. Howard, Linehan, Jacqueline M., Fernandez de Marco, Mar, Brandner, Sebastian, Collinge, John, Klöhn, Peter-Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280992/
https://www.ncbi.nlm.nih.gov/pubmed/22359509
http://dx.doi.org/10.1371/journal.ppat.1002538