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Hemagglutinin from the H5N1 Virus Activates Janus Kinase 3 to Dysregulate Innate Immunity

Highly pathogenic avian influenza viruses (HPAIVs) cause severe disease in humans. There are no effective vaccines or antiviral therapies currently available to control fatal outbreaks due in part to the lack of understanding of virus-mediated immunopathology. In our study, we used hemagglutinin (HA...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Chen, Minhui, Ge, Nanhai, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3280993/
https://www.ncbi.nlm.nih.gov/pubmed/22359619
http://dx.doi.org/10.1371/journal.pone.0031721