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Effects of Inhibiting CoQ(10) Biosynthesis with 4-nitrobenzoate in Human Fibroblasts

Coenzyme Q(10) (CoQ(10)) is a potent lipophilic antioxidant in cell membranes and a carrier of electrons in the mitochondrial respiratory chain. We previously characterized the effects of varying severities of CoQ(10) deficiency on ROS production and mitochondrial bioenergetics in cells harboring ge...

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Detalles Bibliográficos
Autores principales: Quinzii, Catarina M., Tadesse, Saba, Naini, Ali, Hirano, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281033/
https://www.ncbi.nlm.nih.gov/pubmed/22359546
http://dx.doi.org/10.1371/journal.pone.0030606