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Improved Control of Tuberculosis and Activation of Macrophages in Mice Lacking Protein Kinase R

Host factors that microbial pathogens exploit for their propagation are potential targets for therapeuic countermeasures. No host enzyme has been identified whose genetic absence benefits the intact mammalian host in vivo during infection with Mycobacterium tuberculosis (Mtb), the leading cause of d...

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Detalles Bibliográficos
Autores principales: Wu, Kangyun, Koo, Jovanka, Jiang, Xiuju, Chen, Ran, Cohen, Stanley N., Nathan, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281035/
https://www.ncbi.nlm.nih.gov/pubmed/22359543
http://dx.doi.org/10.1371/journal.pone.0030512