Tetrahydrodipicolinate N-Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa: Structure Analysis and Gene Deletion

The diaminopimelic acid pathway of lysine biosynthesis has been suggested to provide attractive targets for the development of novel antibacterial drugs. Here we report the characterization of two enzymes from this pathway in the human pathogen Pseudomonas aeruginosa, utilizing structural biology, b...

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Detalles Bibliográficos
Autores principales: Schnell, Robert, Oehlmann, Wulf, Sandalova, Tatyana, Braun, Yvonne, Huck, Carmen, Maringer, Marko, Singh, Mahavir, Schneider, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281039/
https://www.ncbi.nlm.nih.gov/pubmed/22359568
http://dx.doi.org/10.1371/journal.pone.0031133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281039/
https://www.ncbi.nlm.nih.gov/pubmed/22359568
http://dx.doi.org/10.1371/journal.pone.0031133

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