Cargando…

Morphine Suppresses IFN Signaling Pathway and Enhances AIDS Virus Infection

BACKGROUND: Opioids exert a profound influence on immunomodulation and enhance HIV infection and replication. However, the mechanism(s) of their action remains to be determined. We thus investigated the impact of morphine on the intracellular innate antiviral immunity. METHODOLOGY/PRINCIPAL FINDINGS...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yizhong, Wang, Xu, Ye, Li, Li, Jieliang, Song, Li, Fulambarkar, Nilija, Ho, Wenzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281044/
https://www.ncbi.nlm.nih.gov/pubmed/22359571
http://dx.doi.org/10.1371/journal.pone.0031167