Dehydrocostuslactone Suppresses Angiogenesis In Vitro and In Vivo through Inhibition of Akt/GSK-3β and mTOR Signaling Pathways

The traditional Chinese medicine component dehydrocostuslactone (DHC) isolated from Saussurea costus (Falc.) Lipschitz, has been shown to have anti-cancer activity. Angiogenesis is an essential process in the growth and progression of cancer. In this study, we demonstrated, for the first time, the a...

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Detalles Bibliográficos
Autores principales: Wang, Chih-Ya, Tsai, An-Chi, Peng, Chieh-Yu, Chang, Ya-Ling, Lee, Kuo-Hsiung, Teng, Che-Ming, Pan, Shiow-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281050/
https://www.ncbi.nlm.nih.gov/pubmed/22359572
http://dx.doi.org/10.1371/journal.pone.0031195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281050/
https://www.ncbi.nlm.nih.gov/pubmed/22359572
http://dx.doi.org/10.1371/journal.pone.0031195

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