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Dehydrocostuslactone Suppresses Angiogenesis In Vitro and In Vivo through Inhibition of Akt/GSK-3β and mTOR Signaling Pathways
The traditional Chinese medicine component dehydrocostuslactone (DHC) isolated from Saussurea costus (Falc.) Lipschitz, has been shown to have anti-cancer activity. Angiogenesis is an essential process in the growth and progression of cancer. In this study, we demonstrated, for the first time, the a...
Autores principales: | Wang, Chih-Ya, Tsai, An-Chi, Peng, Chieh-Yu, Chang, Ya-Ling, Lee, Kuo-Hsiung, Teng, Che-Ming, Pan, Shiow-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281050/ https://www.ncbi.nlm.nih.gov/pubmed/22359572 http://dx.doi.org/10.1371/journal.pone.0031195 |
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