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AMP-Activated Protein Kinase Plays an Important Evolutionary Conserved Role in the Regulation of Glucose Metabolism in Fish Skeletal Muscle Cells

AMPK, a master metabolic switch, mediates the observed increase of glucose uptake in locomotory muscle of mammals during exercise. AMPK is activated by changes in the intracellular AMP∶ATP ratio when ATP consumption is stimulated by contractile activity but also by AICAR and metformin, compounds tha...

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Detalles Bibliográficos
Autores principales: Magnoni, Leonardo J., Vraskou, Yoryia, Palstra, Arjan P., Planas, Josep V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281052/
https://www.ncbi.nlm.nih.gov/pubmed/22359576
http://dx.doi.org/10.1371/journal.pone.0031219