A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity

Due to the inexorable invasion of our hospitals and communities by drug-resistant bacteria, there is a pressing need for novel antibacterial agents. Here we report the development of a sensitive and robust but low-tech and inexpensive high-throughput metabolic screen for novel antibiotics. This scre...

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Detalles Bibliográficos
Autores principales: Ymele-Leki, Patrick, Cao, Shugeng, Sharp, Jared, Lambert, Kathleen G., McAdam, Alexander J., Husson, Robert N., Tamayo, Giselle, Clardy, Jon, Watnick, Paula I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281070/
https://www.ncbi.nlm.nih.gov/pubmed/22359585
http://dx.doi.org/10.1371/journal.pone.0031307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281070/
https://www.ncbi.nlm.nih.gov/pubmed/22359585
http://dx.doi.org/10.1371/journal.pone.0031307

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