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A High-Throughput Screen Identifies a New Natural Product with Broad-Spectrum Antibacterial Activity
Due to the inexorable invasion of our hospitals and communities by drug-resistant bacteria, there is a pressing need for novel antibacterial agents. Here we report the development of a sensitive and robust but low-tech and inexpensive high-throughput metabolic screen for novel antibiotics. This scre...
Autores principales: | Ymele-Leki, Patrick, Cao, Shugeng, Sharp, Jared, Lambert, Kathleen G., McAdam, Alexander J., Husson, Robert N., Tamayo, Giselle, Clardy, Jon, Watnick, Paula I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281070/ https://www.ncbi.nlm.nih.gov/pubmed/22359585 http://dx.doi.org/10.1371/journal.pone.0031307 |
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