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Calcineurin Inhibitors Suppress Cytokine Production from Memory T Cells and Differentiation of Naïve T Cells into Cytokine-Producing Mature T Cells

T cells have been classified as belonging to the Th1 or Th2 subsets according to the production of defining cytokines such as IFN-γ and IL-4. The discovery of the Th17 lineage and regulatory T cells shifted the simple concept of the Th1/Th2 balance into a 4-way mechanistic pathway of local and syste...

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Detalles Bibliográficos
Autores principales: Tsuda, Kenshiro, Yamanaka, Keiichi, Kitagawa, Hiroshi, Akeda, Tomoko, Naka, Masanao, Niwa, Kaori, Nakanishi, Takehisa, Kakeda, Masato, Gabazza, Esteban C., Mizutani, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281079/
https://www.ncbi.nlm.nih.gov/pubmed/22359594
http://dx.doi.org/10.1371/journal.pone.0031465