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Calcineurin Inhibitors Suppress Cytokine Production from Memory T Cells and Differentiation of Naïve T Cells into Cytokine-Producing Mature T Cells
T cells have been classified as belonging to the Th1 or Th2 subsets according to the production of defining cytokines such as IFN-γ and IL-4. The discovery of the Th17 lineage and regulatory T cells shifted the simple concept of the Th1/Th2 balance into a 4-way mechanistic pathway of local and syste...
Autores principales: | Tsuda, Kenshiro, Yamanaka, Keiichi, Kitagawa, Hiroshi, Akeda, Tomoko, Naka, Masanao, Niwa, Kaori, Nakanishi, Takehisa, Kakeda, Masato, Gabazza, Esteban C., Mizutani, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281079/ https://www.ncbi.nlm.nih.gov/pubmed/22359594 http://dx.doi.org/10.1371/journal.pone.0031465 |
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