Lack of Renal 11 Beta-Hydroxysteroid Dehydrogenase Type 2 at Birth, a Targeted Temporal Window for Neonatal Glucocorticoid Action in Human and Mice

BACKGROUND: Glucocorticoid hormones play a major role in fetal organ maturation. Yet, excessive glucocorticoid exposure in utero can result in a variety of detrimental effects, such as growth retardation and increased susceptibility to the development of hypertension. To protect the fetus, maternal...

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Detalles Bibliográficos
Autores principales: Martinerie, Laetitia, Pussard, Eric, Meduri, Geri, Delezoide, Anne-Lise, Boileau, Pascal, Lombès, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281096/
https://www.ncbi.nlm.nih.gov/pubmed/22359645
http://dx.doi.org/10.1371/journal.pone.0031949

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281096/
https://www.ncbi.nlm.nih.gov/pubmed/22359645
http://dx.doi.org/10.1371/journal.pone.0031949

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