Glucose Enhances Leptin Signaling through Modulation of AMPK Activity

Leptin exerts its action by binding to and activating the long form of leptin receptors (LEPRb). LEPRb activates JAK2 that subsequently phosphorylates and activates STAT3. The JAK2/STAT3 pathway is required for leptin control of energy balance and body weight. Defects in leptin signaling lead to lep...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Haoran, Jiang, Lin, Carter-Su, Christin, Rui, Liangyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281098/
https://www.ncbi.nlm.nih.gov/pubmed/22359610
http://dx.doi.org/10.1371/journal.pone.0031636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281098/
https://www.ncbi.nlm.nih.gov/pubmed/22359610
http://dx.doi.org/10.1371/journal.pone.0031636

Ejemplares similares