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The Two Different Isoforms of the RSC Chromatin Remodeling Complex Play Distinct Roles in DNA Damage Responses

The RSC chromatin remodeling complex has been implicated in contributing to DNA double-strand break (DSB) repair in a number of studies. Both survival and levels of H2A phosphorylation in response to damage are reduced in the absence of RSC. Importantly, there is evidence for two isoforms of this co...

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Detalles Bibliográficos
Autores principales: Chambers, Anna L., Brownlee, Peter M., Durley, Samuel C., Beacham, Tracey, Kent, Nicholas A., Downs, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281108/
https://www.ncbi.nlm.nih.gov/pubmed/22359657
http://dx.doi.org/10.1371/journal.pone.0032016