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Effects of Deoxycholylglycine, a Conjugated Secondary Bile Acid, on Myogenic Tone and Agonist-Induced Contraction in Rat Resistance Arteries

BACKGROUND: Bile acids (BAs) regulate cardiovascular function via diverse mechanisms. Although in both health and disease serum glycine-conjugated BAs are more abundant than taurine-conjugated BAs, their effects on myogenic tone (MT), a key determinant of systemic vascular resistance (SVR), have not...

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Detalles Bibliográficos
Autores principales: Khurana, Sandeep, Raina, Hema, Pappas, Valeria, Raufman, Jean-Pierre, Pallone, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281111/
https://www.ncbi.nlm.nih.gov/pubmed/22359652
http://dx.doi.org/10.1371/journal.pone.0032006