Cargando…

Lack of Functional Selectin Ligand Interactions Compromises Long Term Tumor Protection by CD8(+) T Cells

Central memory CD8(+) T cells expressing the adhesion molecule CD62L (L-selectin) are potent mediators of anti-cancer immunity due to their ability to proliferate extensively upon antigen re-stimulation. The interaction of selectin with its ligands mediates leukocyte rolling along high endothelial v...

Descripción completa

Detalles Bibliográficos
Autores principales: Stark, Felicity C., Gurnani, Komal, Sad, Subash, Krishnan, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281134/
https://www.ncbi.nlm.nih.gov/pubmed/22359671
http://dx.doi.org/10.1371/journal.pone.0032211