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Lack of Functional Selectin Ligand Interactions Compromises Long Term Tumor Protection by CD8(+) T Cells
Central memory CD8(+) T cells expressing the adhesion molecule CD62L (L-selectin) are potent mediators of anti-cancer immunity due to their ability to proliferate extensively upon antigen re-stimulation. The interaction of selectin with its ligands mediates leukocyte rolling along high endothelial v...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281134/ https://www.ncbi.nlm.nih.gov/pubmed/22359671 http://dx.doi.org/10.1371/journal.pone.0032211 |