Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells

Aurora kinase inhibitors are new mitosis-targeting drugs currently in clinical trials for the treatment of haematological and solid malignancies. However, knowledge of the molecular factors that influence sensitivity and resistance remains limited. Herein, we developed and characterised an in vitro...

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Detalles Bibliográficos
Autores principales: Failes, Timothy W., Mitic, Gorjana, Abdel-Halim, Heba, Po'uha, Sela T., Liu, Marjorie, Hibbs, David E., Kavallaris, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281142/
https://www.ncbi.nlm.nih.gov/pubmed/22359551
http://dx.doi.org/10.1371/journal.pone.0030734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281142/
https://www.ncbi.nlm.nih.gov/pubmed/22359551
http://dx.doi.org/10.1371/journal.pone.0030734

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