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Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells
Aurora kinase inhibitors are new mitosis-targeting drugs currently in clinical trials for the treatment of haematological and solid malignancies. However, knowledge of the molecular factors that influence sensitivity and resistance remains limited. Herein, we developed and characterised an in vitro...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281142/ https://www.ncbi.nlm.nih.gov/pubmed/22359551 http://dx.doi.org/10.1371/journal.pone.0030734 |