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Impairment of the biomechanical compliance of P pili: a novel means of inhibiting uropathogenic bacterial infections?

Gram-negative bacteria often initiate their colonization by use of extended attachment organelles, so called pili. When exposed to force, the rod of helix-like pili has been found to be highly extendable, mainly attributed to uncoiling and recoiling of its quaternary structure. This provides the bac...

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Detalles Bibliográficos
Autores principales: Klinth, Jeanna E., Pinkner, Jerome S., Hultgren, Scott J., Almqvist, Fredrik, Uhlin, Bernt Eric, Axner, Ove
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281203/
https://www.ncbi.nlm.nih.gov/pubmed/22237603
http://dx.doi.org/10.1007/s00249-011-0784-2