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STAT5 is a potent negative regulator of T(FH) cell differentiation

Follicular helper T cells (T(FH) cells) constitute the CD4(+) T cell subset that is specialized to provide help to germinal center (GC) B cells and, consequently, mediate the development of long-lived humoral immunity. T(FH) cell differentiation is driven by the transcription factor Bcl6, and recent...

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Detalles Bibliográficos
Autores principales: Johnston, Robert J., Choi, Youn Soo, Diamond, Jeffrey A., Yang, Jessica A., Crotty, Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281266/
https://www.ncbi.nlm.nih.gov/pubmed/22271576
http://dx.doi.org/10.1084/jem.20111174