Computational prediction of furin cleavage sites by a hybrid method and understanding mechanism underlying diseases

Furin cleaves diverse types of protein precursors in the secretory pathway. The substrates for furin cleavage possess a specific 20-residue recognition sequence motif. In this report, based on the functional characterisation of the 20-residue sequence motif, we developed a furin cleavage site predic...

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Detalles Bibliográficos
Autores principales: Tian, Sun, Huajun, Wang, Wu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281273/
https://www.ncbi.nlm.nih.gov/pubmed/22355773
http://dx.doi.org/10.1038/srep00261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281273/
https://www.ncbi.nlm.nih.gov/pubmed/22355773
http://dx.doi.org/10.1038/srep00261

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