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Near-planar Solution Structures of Mannose-binding Lectin Oligomers Provide Insight on Activation of Lectin Pathway of Complement

The complement system is a fundamental component of innate immunity that orchestrates complex immunological and inflammatory processes. Complement comprises over 30 proteins that eliminate invading microorganisms while maintaining host cell integrity. Protein-carbohydrate interactions play critical...

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Detalles Bibliográficos
Autores principales: Miller, Ami, Phillips, Anna, Gor, Jayesh, Wallis, Russell, Perkins, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281675/
https://www.ncbi.nlm.nih.gov/pubmed/22167201
http://dx.doi.org/10.1074/jbc.M111.320341