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Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines
BACKGROUND: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells, but does not affect normal cells or human leukemic cells, such as MOLT-4 and U937 cells, which are relatively resistant to TRAIL. Three flavonoids extracted from the rhizome of K. pa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281787/ https://www.ncbi.nlm.nih.gov/pubmed/22185222 http://dx.doi.org/10.1186/1756-8722-4-52 |