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Methoxyflavone derivatives modulate the effect of TRAIL-induced apoptosis in human leukemic cell lines

BACKGROUND: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in various tumor cells, but does not affect normal cells or human leukemic cells, such as MOLT-4 and U937 cells, which are relatively resistant to TRAIL. Three flavonoids extracted from the rhizome of K. pa...

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Detalles Bibliográficos
Autores principales: Wudtiwai, Benjawan, Sripanidkulchai, Bungorn, Kongtawelert, Prachya, Banjerdpongchai, Ratana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281787/
https://www.ncbi.nlm.nih.gov/pubmed/22185222
http://dx.doi.org/10.1186/1756-8722-4-52