Structural comparison of tRNA m(1)A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions

BACKGROUND: tRNA m(1)A58 methyltransferases (TrmI) catalyze the transfer of a methyl group from S-adenosyl-L-methionine to nitrogen 1 of adenine 58 in the T-loop of tRNAs from all three domains of life. The m(1)A58 modification has been shown to be essential for cell growth in yeast and for adaptati...

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Detalles Bibliográficos
Autores principales: Guelorget, Amandine, Barraud, Pierre, Tisné, Carine, Golinelli-Pimpaneau, Béatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281791/
https://www.ncbi.nlm.nih.gov/pubmed/22168821
http://dx.doi.org/10.1186/1472-6807-11-48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281791/
https://www.ncbi.nlm.nih.gov/pubmed/22168821
http://dx.doi.org/10.1186/1472-6807-11-48

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