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Structural comparison of tRNA m(1)A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions
BACKGROUND: tRNA m(1)A58 methyltransferases (TrmI) catalyze the transfer of a methyl group from S-adenosyl-L-methionine to nitrogen 1 of adenine 58 in the T-loop of tRNAs from all three domains of life. The m(1)A58 modification has been shown to be essential for cell growth in yeast and for adaptati...
Autores principales: | Guelorget, Amandine, Barraud, Pierre, Tisné, Carine, Golinelli-Pimpaneau, Béatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281791/ https://www.ncbi.nlm.nih.gov/pubmed/22168821 http://dx.doi.org/10.1186/1472-6807-11-48 |
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