Anti-tumor effects of fibroblast growth factor-binding protein (FGF-BP) knockdown in colon carcinoma

BACKGROUND: Fibroblast growth factors FGF-1 and FGF-2 are often upregulated in tumors, but tightly bound to heparan sulphate proteoglycans of the extracellular matrix (ECM). One mechanism of their bioactivation relies on the FGF-binding protein (FGF-BP) which, upon reversible binding to FGF-1 or -2,...

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Detalles Bibliográficos
Autores principales: Schulze, Daniel, Plohmann, Philipp, Höbel, Sabrina, Aigner, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281803/
https://www.ncbi.nlm.nih.gov/pubmed/22111880
http://dx.doi.org/10.1186/1476-4598-10-144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281803/
https://www.ncbi.nlm.nih.gov/pubmed/22111880
http://dx.doi.org/10.1186/1476-4598-10-144

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