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Targeted Expression of Cre Recombinase Provokes Placental-Specific DNA Recombination in Transgenic Mice
BACKGROUND: Inadequate placental development is associated with a high incidence of early embryonic lethality and serious pregnancy disorders in both humans and mice. However, the lack of well-defined trophoblast-specific gene regulatory elements has hampered investigations regarding the role of spe...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281813/ https://www.ncbi.nlm.nih.gov/pubmed/22363401 http://dx.doi.org/10.1371/journal.pone.0029236 |