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DRB1*03:01 Haplotypes: Differential Contribution to Multiple Sclerosis Risk and Specific Association with the Presence of Intrathecal IgM Bands

BACKGROUND: Multiple sclerosis (MS) is a multifactorial disease with a genetic basis. The strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region. However, except for the DRB1*15:01 allele, the main risk factor associated to MS so far, no consistent effect has been de...

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Detalles Bibliográficos
Autores principales: de la Concha, Emilio G., Cavanillas, María L., Cénit, M. Carmen, Urcelay, Elena, Arroyo, Rafael, Fernández, Óscar, Álvarez-Cermeño, José C., Leyva, Laura, Villar, Luisa M., Núñez, Concepción
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281895/
https://www.ncbi.nlm.nih.gov/pubmed/22363536
http://dx.doi.org/10.1371/journal.pone.0031018