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DRB1*03:01 Haplotypes: Differential Contribution to Multiple Sclerosis Risk and Specific Association with the Presence of Intrathecal IgM Bands
BACKGROUND: Multiple sclerosis (MS) is a multifactorial disease with a genetic basis. The strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region. However, except for the DRB1*15:01 allele, the main risk factor associated to MS so far, no consistent effect has been de...
Autores principales: | de la Concha, Emilio G., Cavanillas, María L., Cénit, M. Carmen, Urcelay, Elena, Arroyo, Rafael, Fernández, Óscar, Álvarez-Cermeño, José C., Leyva, Laura, Villar, Luisa M., Núñez, Concepción |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281895/ https://www.ncbi.nlm.nih.gov/pubmed/22363536 http://dx.doi.org/10.1371/journal.pone.0031018 |
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