Loss of CCDC6 Affects Cell Cycle through Impaired Intra-S-Phase Checkpoint Control

In most cancers harboring Ccdc6 gene rearrangements, like papillary thyroid tumors or myeloproliferative disorders, the product of the normal allele is supposed to be functionally impaired or absent. To address the consequence of the loss of CCDC6 expression, we applied lentiviral shRNA in several c...

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Detalles Bibliográficos
Autores principales: Thanasopoulou, Angeliki, Stravopodis, Dimitrios J., Dimas, Konstantinos S., Schwaller, Juerg, Anastasiadou, Ema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281900/
https://www.ncbi.nlm.nih.gov/pubmed/22363533
http://dx.doi.org/10.1371/journal.pone.0031007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281900/
https://www.ncbi.nlm.nih.gov/pubmed/22363533
http://dx.doi.org/10.1371/journal.pone.0031007

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