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Loss of CCDC6 Affects Cell Cycle through Impaired Intra-S-Phase Checkpoint Control
In most cancers harboring Ccdc6 gene rearrangements, like papillary thyroid tumors or myeloproliferative disorders, the product of the normal allele is supposed to be functionally impaired or absent. To address the consequence of the loss of CCDC6 expression, we applied lentiviral shRNA in several c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281900/ https://www.ncbi.nlm.nih.gov/pubmed/22363533 http://dx.doi.org/10.1371/journal.pone.0031007 |