Metallothionein (MT) -I and MT-II Expression Are Induced and Cause Zinc Sequestration in the Liver after Brain Injury

Experiments with transgenic over-expressing, and null mutant mice have determined that metallothionein-I and -II (MT-I/II) are protective after brain injury. MT-I/II is primarily a zinc-binding protein and it is not known how it provides neuroprotection to the injured brain or where MT-I/II acts to...

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Detalles Bibliográficos
Autores principales: Pankhurst, Michael W., Gell, David A., Butler, Chris W., Kirkcaldie, Matthew T. K., West, Adrian K., Chung, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281953/
https://www.ncbi.nlm.nih.gov/pubmed/22363575
http://dx.doi.org/10.1371/journal.pone.0031185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281953/
https://www.ncbi.nlm.nih.gov/pubmed/22363575
http://dx.doi.org/10.1371/journal.pone.0031185

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