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Metallothionein (MT) -I and MT-II Expression Are Induced and Cause Zinc Sequestration in the Liver after Brain Injury
Experiments with transgenic over-expressing, and null mutant mice have determined that metallothionein-I and -II (MT-I/II) are protective after brain injury. MT-I/II is primarily a zinc-binding protein and it is not known how it provides neuroprotection to the injured brain or where MT-I/II acts to...
Autores principales: | Pankhurst, Michael W., Gell, David A., Butler, Chris W., Kirkcaldie, Matthew T. K., West, Adrian K., Chung, Roger S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281953/ https://www.ncbi.nlm.nih.gov/pubmed/22363575 http://dx.doi.org/10.1371/journal.pone.0031185 |
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