Mitosis Phase Enrichment with Identification of Mitotic Centromere-Associated Kinesin As a Therapeutic Target in Castration-Resistant Prostate Cancer

The recently described transcriptomic switch to a mitosis program in castration-resistant prostate cancer (CRPC) suggests that mitotic proteins may be rationally targeted at this lethal stage of the disease. In this study, we showed upregulation of the mitosis-phase at the protein level in our cohor...

Descripción completa

Detalles Bibliográficos
Autores principales: Sircar, Kanishka, Huang, Heng, Hu, Limei, Liu, Yuexin, Dhillon, Jasreman, Cogdell, David, Aprikian, Armen, Efstathiou, Eleni, Navone, Nora, Troncoso, Patricia, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281954/
https://www.ncbi.nlm.nih.gov/pubmed/22363599
http://dx.doi.org/10.1371/journal.pone.0031259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281954/
https://www.ncbi.nlm.nih.gov/pubmed/22363599
http://dx.doi.org/10.1371/journal.pone.0031259

Ejemplares similares