High Glucose Decreases Expression and Activity of p-glycoprotein in Cultured Human Retinal Pigment Epithelium Possibly through iNOS Induction

Inhibition of p-glycoprotein under hyperglycemic conditions has been reported in various barrier tissues including blood-brain barrier, intestine, and kidney, and has been linked to significant clinical complications. However, whether this is also true for the outer blood-retinal barrier constituted...

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Detalles Bibliográficos
Autores principales: Zhang, Yuehong, Li, Chunmei, Sun, Xuerong, Kuang, Xielan, Ruan, Xiangcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281955/
https://www.ncbi.nlm.nih.gov/pubmed/22363694
http://dx.doi.org/10.1371/journal.pone.0031631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281955/
https://www.ncbi.nlm.nih.gov/pubmed/22363694
http://dx.doi.org/10.1371/journal.pone.0031631

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