Activating Transcription Factor 4 Confers a Multidrug Resistance Phenotype to Gastric Cancer Cells through Transactivation of SIRT1 Expression

BACKGROUND: Multidrug resistance (MDR) in gastric cancer remains a major challenge to clinical treatment. Activating transcription factor 4 (ATF4) is a stress response gene involved in homeostasis and cellular protection. However, the expression and function of ATF4 in gastric cancer MDR remains unk...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Hongwu, Xia, Limin, Zhang, Yongguo, Wang, Honghong, Xu, Wenjing, Hu, Hao, Wang, Jing, Xin, Jing, Gang, Yi, Sha, Sumei, Xu, Bin, Fan, Daiming, Nie, Yongzhan, Wu, Kaichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281959/
https://www.ncbi.nlm.nih.gov/pubmed/22363646
http://dx.doi.org/10.1371/journal.pone.0031431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281959/
https://www.ncbi.nlm.nih.gov/pubmed/22363646
http://dx.doi.org/10.1371/journal.pone.0031431

Ejemplares similares