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Selective inhibition of intra-alveolar p55 TNF receptor attenuates ventilator-induced lung injury
BACKGROUND: Tumour necrosis factor (TNF) is upregulated in the alveolar space early in the course of ventilator-induced lung injury (VILI). Studies in genetically modified mice indicate that the two TNF receptors play opposing roles during injurious high-stretch mechanical ventilation, with p55 prom...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282043/ https://www.ncbi.nlm.nih.gov/pubmed/22156959 http://dx.doi.org/10.1136/thoraxjnl-2011-200590 |