Selective inhibition of intra-alveolar p55 TNF receptor attenuates ventilator-induced lung injury

BACKGROUND: Tumour necrosis factor (TNF) is upregulated in the alveolar space early in the course of ventilator-induced lung injury (VILI). Studies in genetically modified mice indicate that the two TNF receptors play opposing roles during injurious high-stretch mechanical ventilation, with p55 prom...

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Detalles Bibliográficos
Autores principales: Bertok, Szabolcs, Wilson, Michael R, Morley, Peter J, de Wildt, Ruud, Bayliffe, Andrew, Takata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acute Lung Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282043/
https://www.ncbi.nlm.nih.gov/pubmed/22156959
http://dx.doi.org/10.1136/thoraxjnl-2011-200590

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