Geminin overexpression induces mammary tumors via suppressing cytokinesis

Aneuploidy plays an important role in the development of cancer. Here, we uncovered an oncogenic role for geminin in mitotic cells. In addition to chromatin, tyrosine phosphorylated geminin also localizes to centrosome, spindle, cleavage furrow and midbody during mitosis. Geminin binding to Aurora B...

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Detalles Bibliográficos
Autores principales: Blanchard, Zannel, Malik, Rohit, Mullins, Nicole, Maric, Christine, Luk, Hugh, Horio, David, Hernandez, Brenda, Killeen, Jeffrey, ElShamy, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282064/
https://www.ncbi.nlm.nih.gov/pubmed/22184288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282064/
https://www.ncbi.nlm.nih.gov/pubmed/22184288

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