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Genome-wide analysis discloses reversal of the hypoxia-induced changes of gene expression in colon cancer cells by zinc supplementation

Hypoxia-inducible factor 1 (HIF-1), the major transcription factor specifically activated during hypoxia, regulates genes involved in critical aspects of cancer biology, including angiogenesis, cell proliferation, glycolysis and invasion. The HIF-1a subunit is stabilized by low oxygen, genetic alter...

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Detalles Bibliográficos
Autores principales: Sheffer, Michal, Simon, Amos J., Jacob-Hirsch, Jasmine, Rechavi, Gideon, Domany, Eytan, Givol, David, D’Orazi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282077/
https://www.ncbi.nlm.nih.gov/pubmed/22202117