Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1)

RNAi screening holds the promise of systemizing the search for combination therapeutic strategies. Here we performed a pooled shRNA library screen to look for promising targets to inhibit in combination with inhibition of the mitotic regulator polo-like kinase (PLK1). The library contained ~4,500 sh...

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Detalles Bibliográficos
Autores principales: Liu-Sullivan, Nancy, Zhang, Jianping, Bakleh, Amy, Marchica, John, Li, Jinyu, Siolas, Despina, Laquerre, Sylvie, Degenhardt, Yan Y., Wooster, Richard, Chang, Kenneth, Hannon, Gregory F., Powers, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282082/
https://www.ncbi.nlm.nih.gov/pubmed/22248814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282082/
https://www.ncbi.nlm.nih.gov/pubmed/22248814

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